STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M5GC32_DACPDSIR2-domain-containing protein. (532 aa)    
Predicted Functional Partners:
M5GBS1_DACPD
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.930
M5FZZ2_DACPD
NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.
  
 
0.893
M5G727_DACPD
Pyrazinamidase/nicotinamidase-like protein.
   
 0.878
M5G7Z7_DACPD
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
   
 0.877
M5G228_DACPD
tRNA guanosine-2'-O-methyltransferase.
    
 0.861
M5GCY8_DACPD
Nudix hydrolase domain-containing protein.
    
 0.852
M5G0D7_DACPD
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.847
M5G6P2_DACPD
DHS-like NAD/FAD-binding domain-containing protein.
  
 
0.847
M5FNF7_DACPD
ATP-NAD kinase.
  
 
 0.826
M5G7R6_DACPD
Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family.
    
 0.823
Your Current Organism:
Dacryopinax primogenitus
NCBI taxonomy Id: 1858805
Other names: D. primogenitus, DJM 731, DJM-731 SS1, Dacryopinax primogenitus D. J. McLaughlin & E. G. McLaughlin, 2016, Dacryopinax sp. DJM-731 SS1, Dacryopinax sp. MIN 862738, MIN 929365
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.