STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
M5GDF4_DACPDDehydrogenase E1 and transketolase domain-containing protein 1. (933 aa)    
Predicted Functional Partners:
M5G257_DACPD
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.988
M5G0C3_DACPD
Dihydrolipoyl dehydrogenase.
  
 0.968
M5FQD5_DACPD
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.959
M5FX45_DACPD
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.959
M5G1P7_DACPD
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.958
M5GAG0_DACPD
Single hybrid motif-containing protein.
  
 0.958
M5GBM1_DACPD
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.926
M5G2V5_DACPD
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 
 0.924
M5FMX5_DACPD
Citrate synthase.
  
 0.912
M5FQP0_DACPD
CoA_binding domain-containing protein.
  
 0.912
Your Current Organism:
Dacryopinax primogenitus
NCBI taxonomy Id: 1858805
Other names: D. primogenitus, DJM 731, DJM-731 SS1, Dacryopinax primogenitus D. J. McLaughlin & E. G. McLaughlin, 2016, Dacryopinax sp. DJM-731 SS1, Dacryopinax sp. MIN 862738, MIN 929365
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