M5GET5_DACPD protein (Dacryopinax primogenitus)

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

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[Homology]

Score

M5GET5_DACPD

DUF383-domain-containing protein. (437 aa)

Predicted Functional Partners:

M5FWU9_DACPD

0.910

M5FUX2_DACPD

0.825

M5G4Z6_DACPD

0.763

TRM82

0.722

M5G2K6_DACPD

0.720

M5GGQ5_DACPD

0.712

M5FWA1_DACPD

0.698

M5GCQ6_DACPD

0.697

M5G553_DACPD

0.695

M5FXR9_DACPD

0.694

Your Current Organism:

Dacryopinax primogenitus

NCBI taxonomy Id: 1858805
Other names: D. primogenitus, DJM 731, DJM-731 SS1, Dacryopinax primogenitus D. J. McLaughlin & E. G. McLaughlin, 2016, Dacryopinax sp. DJM-731 SS1, Dacryopinax sp. MIN 862738, MIN 929365

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
M5FUX2_DACPD	M5G4Z6_DACPD	M5FUX2	M5G4Z6	Uncharacterized protein.	NUC189-domain-containing protein.	0.414
M5FUX2_DACPD	M5GET5_DACPD	M5FUX2	M5GET5	Uncharacterized protein.	DUF383-domain-containing protein.	0.825
M5FWA1_DACPD	M5FXR9_DACPD	M5FWA1	M5FXR9	WD40 repeat-like protein.	TRASH domain-containing protein.	0.825
M5FWA1_DACPD	M5G2K6_DACPD	M5FWA1	M5G2K6	WD40 repeat-like protein.	WD40 repeat-like protein.	0.906
M5FWA1_DACPD	M5G4Z6_DACPD	M5FWA1	M5G4Z6	WD40 repeat-like protein.	NUC189-domain-containing protein.	0.843
M5FWA1_DACPD	M5G553_DACPD	M5FWA1	M5G553	WD40 repeat-like protein.	Ribosomal protein L1.	0.919
M5FWA1_DACPD	M5GCQ6_DACPD	M5FWA1	M5GCQ6	WD40 repeat-like protein.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.867
M5FWA1_DACPD	M5GET5_DACPD	M5FWA1	M5GET5	WD40 repeat-like protein.	DUF383-domain-containing protein.	0.698
M5FWA1_DACPD	M5GGQ5_DACPD	M5FWA1	M5GGQ5	WD40 repeat-like protein.	Brix-domain-containing protein.	0.887
M5FWA1_DACPD	TRM82	M5FWA1	M5G4Y0	WD40 repeat-like protein.	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	0.731
M5FWU9_DACPD	M5G4Z6_DACPD	M5FWU9	M5G4Z6	TPR-like protein.	NUC189-domain-containing protein.	0.424
M5FWU9_DACPD	M5GET5_DACPD	M5FWU9	M5GET5	TPR-like protein.	DUF383-domain-containing protein.	0.910
M5FWU9_DACPD	M5GGQ5_DACPD	M5FWU9	M5GGQ5	TPR-like protein.	Brix-domain-containing protein.	0.414
M5FXR9_DACPD	M5FWA1_DACPD	M5FXR9	M5FWA1	TRASH domain-containing protein.	WD40 repeat-like protein.	0.825
M5FXR9_DACPD	M5G2K6_DACPD	M5FXR9	M5G2K6	TRASH domain-containing protein.	WD40 repeat-like protein.	0.743
M5FXR9_DACPD	M5G4Z6_DACPD	M5FXR9	M5G4Z6	TRASH domain-containing protein.	NUC189-domain-containing protein.	0.843
M5FXR9_DACPD	M5G553_DACPD	M5FXR9	M5G553	TRASH domain-containing protein.	Ribosomal protein L1.	0.986
M5FXR9_DACPD	M5GCQ6_DACPD	M5FXR9	M5GCQ6	TRASH domain-containing protein.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.962
M5FXR9_DACPD	M5GET5_DACPD	M5FXR9	M5GET5	TRASH domain-containing protein.	DUF383-domain-containing protein.	0.694
M5FXR9_DACPD	M5GGQ5_DACPD	M5FXR9	M5GGQ5	TRASH domain-containing protein.	Brix-domain-containing protein.	0.994

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.968

expected number of edges:

11

PPI enrichment p-value:

3.84e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006525

Arginine metabolic process

11 of 34

2.23

8.23

2.82e-21

GO:0006526

Arginine biosynthetic process

9 of 17

2.45

8.04

4.90e-18

GO:0006591

Ornithine metabolic process

4 of 6

2.55

3.56

1.65e-07

GO:0042450

Arginine biosynthetic process via ornithine

2 of 2

2.72

1.57

0.0014

GO:0044205

De novo UMP biosynthetic process

2 of 7

2.18

1.12

0.0079

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0103045

Methione N-acyltransferase activity

2 of 2

2.72

0.93

0.0203

GO:0004088

Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

2 of 2

2.72

0.93

0.0203

GO:0004042

acetyl-CoA:L-glutamate N-acetyltransferase activity

2 of 2

2.72

0.93

0.0203

GO:0016774

Phosphotransferase activity, carboxyl group as acceptor

2 of 7

2.18

0.82

0.0303

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

3 of 51

1.49

0.73

0.0303

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1829

0.5

0.42

0.00052

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1505

Arginine biosynthesis, and Amino acid antiporter

9 of 15

2.5

8.22

4.37e-18

CL:1510

Arginine biosynthesis

6 of 6

2.72

6.12

1.70e-12

CL:1367

Cellular amino acid biosynthetic process, and Ribonucleoside monophosphate biosynthetic process

11 of 152

1.58

3.6

3.78e-15

CL:1525

Amino acid antiporter, and Arginine catabolic process to ornithine

2 of 5

2.33

1.03

0.0127

CL:1578

Pyrimidine biosynthesis, and Dihydroorotase, conserved site

2 of 6

2.25

0.99

0.0148

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pfn00220

Arginine biosynthesis

9 of 36

2.12

6.25

3.12e-16

pfn00250

Alanine, aspartate and glutamate metabolism

4 of 39

1.74

1.95

3.78e-05

pfn01230

Biosynthesis of amino acids

7 of 179

1.32

1.75

6.17e-07

pfn01210

2-Oxocarboxylic acid metabolism

4 of 51

1.62

1.75

6.84e-05

pfn01110

Biosynthesis of secondary metabolites

8 of 614

0.84

0.78

6.84e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005951

Carbamoyl-phosphate synthase complex

2 of 2

2.72

1.18

0.0073

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0055

Arginine biosynthesis

9 of 13

2.56

8.87

2.96e-19

KW-0963

Cytoplasm

8 of 311

1.13

1.38

8.14e-07

KW-0665

Pyrimidine biosynthesis

2 of 10

2.03

1.0

0.0124

KW-0436

Ligase

3 of 73

1.34

0.8

0.0152

KW-0808

Transferase

5 of 407

0.81

0.51

0.0216

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00696

Amino acid kinase family

3 of 6

2.42

1.85

0.00035

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036393

Acetylglutamate kinase-like superfamily

3 of 6

2.42

1.71

0.00065

IPR001048

Aspartate/glutamate/uridylate kinase

3 of 6

2.42

1.71

0.00065

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