STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OFI49385.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (718 aa)    
Predicted Functional Partners:
OFI49386.1
Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 0.999
OFI49384.1
NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.984
OFI49682.1
Ribonucleotide reductase stimulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NrdI family.
 
  
 0.980
OFI48163.1
NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.958
OFI48178.1
Thiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.880
OFI48808.1
NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.861
OFI49515.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.859
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.822
OFI48602.1
Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.807
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.791
Your Current Organism:
Floricoccus tropicus
NCBI taxonomy Id: 1859473
Other names: Anthococcus sp. DF1, F. tropicus, Floricoccus tropicus Chuah et al. 2017, JCM 31733, LMG 29833, LMG:29833, Lactobacillales bacterium DF1, Lactobacillales bacterium HibF2, Lactobacillales bacterium HibF5, Streptococcus sp. DF1, Streptococcus sp. HibF2, Streptococcus sp. HibF5, strain DF1
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