STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFA45731.1Trp operon repressor family. (108 aa)    
Predicted Functional Partners:
SFA45727.1
Protein of unknown function.
 
    0.850
SFA45719.1
Adenine deaminase.
       0.678
pcrB
Putative glycerol-1-phosphate prenyltransferase; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
 
     0.644
SFA45716.1
Protein of unknown function.
       0.524
fapR
Acyl-coenzyme A thioesterase PaaI, contains HGG motif; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
  
     0.512
SFA45742.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
       0.485
ligA
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.465
SFA45748.1
Protein involved in sex pheromone biosynthesis.
       0.457
Your Current Organism:
Parageobacillus thermantarcticus
NCBI taxonomy Id: 186116
Other names: BGSC 20A1, Bacillus thermantarcticus, Bacillus thermantarcticus corrig. Nicolaus et al. 2002, Bacillus thermoantarcticus, DSM 9572, Geobacillus sp. R-35644, Geobacillus thermantarcticus, Geobacillus thermantarcticus (Nicolaus et al. 2002) Coorevits et al. 2012, LMG 23032, LMG:23032, P. thermantarcticus, strain M1, strain R-35644
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