node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFA38905.1 | SFA49353.1 | SAMN05192569_1001203 | SAMN05192569_10215 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.889 |
SFA38905.1 | SFA49356.1 | SAMN05192569_1001203 | SAMN05192569_10216 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.866 |
SFA38905.1 | SFA49359.1 | SAMN05192569_1001203 | SAMN05192569_10217 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.990 |
SFA38905.1 | SFA49364.1 | SAMN05192569_1001203 | SAMN05192569_10218 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 4-amino-4-deoxychorismate lyase. | 0.657 |
SFA38905.1 | folE | SAMN05192569_1001203 | SAMN05192569_101172 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I. | 0.616 |
SFA38905.1 | ilvE | SAMN05192569_1001203 | SAMN05192569_1001230 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.657 |
SFA38905.1 | trpE-2 | SAMN05192569_1001203 | SAMN05192569_102110 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Para-aminobenzoate synthetase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high [...] | 0.463 |
SFA49347.1 | SFA49350.1 | SAMN05192569_10213 | SAMN05192569_10214 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | DNA-binding transcriptional regulator, XRE-family HTH domain. | 0.879 |
SFA49347.1 | SFA49353.1 | SAMN05192569_10213 | SAMN05192569_10215 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.776 |
SFA49347.1 | SFA49356.1 | SAMN05192569_10213 | SAMN05192569_10216 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.768 |
SFA49347.1 | SFA49359.1 | SAMN05192569_10213 | SAMN05192569_10217 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.806 |
SFA49347.1 | SFA49364.1 | SAMN05192569_10213 | SAMN05192569_10218 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 4-amino-4-deoxychorismate lyase. | 0.780 |
SFA49347.1 | SFA49368.1 | SAMN05192569_10213 | SAMN05192569_10219 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Aminodeoxychorismate synthase, glutamine amidotransferase subunit. | 0.769 |
SFA49347.1 | trpE-2 | SAMN05192569_10213 | SAMN05192569_102110 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Para-aminobenzoate synthetase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high [...] | 0.744 |
SFA49350.1 | SFA49347.1 | SAMN05192569_10214 | SAMN05192569_10213 | DNA-binding transcriptional regulator, XRE-family HTH domain. | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.879 |
SFA49350.1 | SFA49353.1 | SAMN05192569_10214 | SAMN05192569_10215 | DNA-binding transcriptional regulator, XRE-family HTH domain. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.815 |
SFA49350.1 | SFA49356.1 | SAMN05192569_10214 | SAMN05192569_10216 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.805 |
SFA49350.1 | SFA49359.1 | SAMN05192569_10214 | SAMN05192569_10217 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.842 |
SFA49350.1 | SFA49364.1 | SAMN05192569_10214 | SAMN05192569_10218 | DNA-binding transcriptional regulator, XRE-family HTH domain. | 4-amino-4-deoxychorismate lyase. | 0.853 |
SFA49350.1 | SFA49368.1 | SAMN05192569_10214 | SAMN05192569_10219 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Aminodeoxychorismate synthase, glutamine amidotransferase subunit. | 0.808 |