OLU46624.1 protein (Dubosiella newyorkensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

OLU46624.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (481 aa)

Predicted Functional Partners:

OLU46625.1

0.708

OLU44019.1

0.629

OLU46626.1

0.457

OLU46627.1

0.457

OLU46623.1

0.420

Your Current Organism:

Dubosiella newyorkensis

NCBI taxonomy Id: 1862672
Other names: ATCC TSD-64, D. newyorkensis, DSM 103457, Dubosiella newyorkensis Cox et al. 2017, Erysipelotrichaceae bacterium NYU-BL-A4, strain NYU-BL-A4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OLU44019.1	OLU46624.1	BO225_11220	BO225_05485	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.629
OLU46623.1	OLU46624.1	BO225_05480	BO225_05485	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.420
OLU46623.1	OLU46625.1	BO225_05480	BO225_05490	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.445
OLU46624.1	OLU44019.1	BO225_05485	BO225_11220	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.629
OLU46624.1	OLU46623.1	BO225_05485	BO225_05480	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.420
OLU46624.1	OLU46625.1	BO225_05485	BO225_05490	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.708
OLU46624.1	OLU46626.1	BO225_05485	BO225_05495	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.457
OLU46624.1	OLU46627.1	BO225_05485	BO225_05500	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 'phage' integrase family.	0.457
OLU46625.1	OLU46623.1	BO225_05490	BO225_05480	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.445
OLU46625.1	OLU46624.1	BO225_05490	BO225_05485	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.708
OLU46625.1	OLU46626.1	BO225_05490	BO225_05495	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.523
OLU46625.1	OLU46627.1	BO225_05490	BO225_05500	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 'phage' integrase family.	0.556
OLU46626.1	OLU46624.1	BO225_05495	BO225_05485	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.457
OLU46626.1	OLU46625.1	BO225_05495	BO225_05490	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.523
OLU46626.1	OLU46627.1	BO225_05495	BO225_05500	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 'phage' integrase family.	0.773
OLU46627.1	OLU46624.1	BO225_05500	BO225_05485	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 'phage' integrase family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.457
OLU46627.1	OLU46625.1	BO225_05500	BO225_05490	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 'phage' integrase family.	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.556
OLU46627.1	OLU46626.1	BO225_05500	BO225_05495	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 'phage' integrase family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.773

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.889

expected number of edges:

12

PPI enrichment p-value:

6.09e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006468

Protein phosphorylation

4 of 27

1.49

1.12

0.0029

GO:0036211

Protein modification process

5 of 53

1.29

1.05

0.0018

GO:0016310

Phosphorylation

6 of 90

1.14

0.93

0.0018

GO:0071766

Actinobacterium-type cell wall biogenesis

2 of 3

2.14

0.87

0.0240

GO:0000271

Polysaccharide biosynthetic process

3 of 21

1.47

0.8

0.0203

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004674

Protein serine/threonine kinase activity

4 of 6

2.14

2.27

3.24e-05

GO:0016301

Kinase activity

6 of 76

1.22

1.19

0.00019

GO:0106310

Protein serine kinase activity

2 of 2

2.32

1.05

0.0115

GO:0031177

Phosphopantetheine binding

2 of 3

2.14

1.01

0.0127

GO:0140096

Catalytic activity, acting on a protein

5 of 116

0.95

0.63

0.0115

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:766

Mixed, incl. Protein kinase domain, and Forkhead associated domain

4 of 12

1.84

1.7

0.00027

CL:769

PASTA domain, and Forkhead associated domain

3 of 6

2.02

1.55

0.00091

CL:2820

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Polysaccharide biosynthetic process

5 of 46

1.36

1.25

0.00050

CL:2858

Polysaccharide biosynthetic process, and Glycosyl transferase, family 1

3 of 18

1.54

1.07

0.0047

CL:2822

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Polysaccharide biosynthetic process

4 of 36

1.37

1.06

0.0026

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033172

Gas vesicle shell

2 of 2

2.32

0.84

0.0289

GOCC:0034081

Polyketide synthase complex

2 of 3

2.14

0.83

0.0289

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000719

Protein kinase domain

4 of 5

2.22

2.28

3.59e-05

IPR011009

Protein kinase-like domain superfamily

4 of 11

1.88

1.79

0.00019

IPR008271

Serine/threonine-protein kinase, active site

3 of 3

2.32

1.73

0.00055

IPR005543

PASTA domain

3 of 3

2.32

1.73

0.00055

IPR005702

Exopolysaccharide synthesis protein

2 of 2

2.32

0.87

0.0253

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00740

PASTA

3 of 3

2.32

2.03

0.00014

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