STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0014Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. (128 aa)    
Predicted Functional Partners:
PF0015
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
 
 0.990
psmB1
Proteasome, subunit beta (multicatalytic endopeptidase complex beta subunit); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
      
 0.760
psmB2
Proteasome, subunit beta (multicatalytic endopeptidase complex beta subunit); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
      
 0.760
PF0013
Transposase; Function Code: 15.3 Other Categories: Transposon-related functions.
       0.689
vapC
Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
      
 0.601
mtnP
5'-methylthioadenosine phosphorylase I; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
       0.563
psmA
Proteasome, subunit alpha (multicatalytic endopeptidase complex alpha subunit); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
      
 0.422
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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