STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0116Putative multiple sugar transport protein; Function Code: 14.1 Transport and Binding Proteins: General. (364 aa)    
Predicted Functional Partners:
PF0117
Function Code: 14.4 Transport and Binding Proteins: Carbohydrates, organic alcohols, and acids.
 
  
 0.974
PF0118
Putative ABC transporter permease protein; Function Code: 14.4 Transport and Binding Proteins: Carbohydrates, organic alcohols, and acids.
 
  
 0.973
PF0119
Putative perplasmic sugar binding protein; Function Code: 14.4 Transport and Binding proteins: Carbohyrates, Organic alcohol, and acids.
 
  
 0.961
wtpB
Sulfate/thiosulfate transport protein homolog cyst; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane.
 
 0.720
PF1969
Sugar ABC transporter, permease protein; Function Code: 14.4 Transport and Binding Proteins: Carbohydrates, organic alcohols, and acids.
 
   
 0.656
PF1968
Function Code: 14.4 Transport and Binding Proteins: Carbohydrates, organic alcohols, and acids.
 
   
 0.574
pan
ATP-dependent 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promo [...]
       0.562
engB
GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation.
       0.438
PF1749
Putative sulfate transport integral membrane protein; Function Code: 14.3 Transport and Binding Proteins: Anions.
 
    0.436
PF1740
Trehalose/maltose transport inner membrane protein; Function Code: 14.4 Transport and Binding Proteins: Carbohydrates, organic alcohols, and acids; (malF).
 
   
 0.429
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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