STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0395Oxetanocin-like protein; Function Code: 16.0 Unknown; related to oxetanocin a biosynthetic enzyme [bacillus megaterium]. (176 aa)    
Predicted Functional Partners:
PF0396
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.845
PF0394
UDP-n-acetylglucosamine-dolichyl-phosphate n-acetylglucosaminephosphotransferase; Function Code: 3.2 Cell Envelope: Surface polysaccharides, lipopolysaccharides and antigens.
 
     0.808
PF0397
GTP-binding protein homologue; Function Code: 16 Unknown:.
       0.712
pcn
Pcna sliding clamp (proliferating-cell nuclear antigen); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. Unlike its eukaryotic paralog, loads on circular DNA without the replication factor C (RFC) clamp loader, although RFC greatly increases loading efficiency. Stimulates the ATPase activity of replication factor C (RFC) in the presence of ssDNA. Stimulates the helicase activity of Hel308 and may alter its substrate specificity.
 
     0.499
PF0211
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
   
    0.487
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
 
     0.482
PF0432
Putative sugar-catabolism phosphotransferase; Function Code: 6.9 Energy Metabolism: Sugars.
 
  
 0.448
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.