STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF1861Endo-1,4-beta-glucanase-like protein; Hydrolyzes di-, tri- and tetrapeptides with a lysine as the N-terminal amino acid and with Gly, Lys, Ala, Phe or Glu in the second position; Belongs to the peptidase M42 family. (346 aa)    
Predicted Functional Partners:
PF1859
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.799
amzA
Hypothetical protein; Probable zinc metalloprotease whose natural substrate is unknown.
       0.799
PF0077
Biotin operon repressor/biotin--[acetyl CoA carboxylase] ligase; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS; (birA).
     
 0.629
PF2038
Cob(i)alamin adenosyltransferase; Function Code: 2.1 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: General.
      
 0.601
PF0138
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
      
 0.600
PF0144
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
      
 0.600
PF1500
Function Code: 16.4 Hypothetical.
      
 0.600
PF1987
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
      
 0.600
PF0056
Putative carbohydrate binding protein; Function Code: 16.0 Unknown.
      
 0.538
hypA
Hydrogenase expression/formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
      
 0.471
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.