STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (341 aa)    
Predicted Functional Partners:
OED37039.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.991
OED35766.1
uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the precorrin methyltransferase family.
 
 0.977
OED37517.1
Oxygen-independent coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
 
 0.959
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.955
OED38220.1
Thiamine biosynthesis protein ThiH; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.778
bioB
Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
   
 
 0.776
OED35315.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.742
OED35781.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.630
OED34207.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.624
OED36210.1
NAD(P)H nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.613
Your Current Organism:
PVC group bacterium
NCBI taxonomy Id: 1868283
Other names: P. group bacterium (ex Bugula neritina AB1), PVC group bacterium (ex Bugula neritina AB1)
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