STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OED34752.1Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)    
Predicted Functional Partners:
OED34751.1
Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ilvD
Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family.
 
 0.988
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.984
OED35603.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.975
OED34736.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.914
OED35782.1
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LeuD family.
  
 
 0.912
OED37110.1
Catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.905
OED35187.1
Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.854
OED35788.1
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.
  
 
 0.829
OED35105.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.825
Your Current Organism:
PVC group bacterium
NCBI taxonomy Id: 1868283
Other names: P. group bacterium (ex Bugula neritina AB1), PVC group bacterium (ex Bugula neritina AB1)
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