STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEPHS1Selenide, water dikinase 1 isoform X1. (392 aa)    
Predicted Functional Partners:
SEPSECS
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
     
 0.898
SCLY
Selenocysteine lyase.
    
 0.891
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
    
 0.880
TXNRD2
Thioredoxin reductase 2, mitochondrial.
  
 
 0.858
TXNRD3
Thioredoxin reductase 3 isoform X1.
  
 
 0.858
TXNRD1
Thioredoxin reductase 1, cytoplasmic.
  
 
 0.851
NFS1
LOW QUALITY PROTEIN: cysteine desulfurase, mitochondrial.
    
 0.749
ENSTSYP00000026545
annotation not available
    
 0.749
ENSTSYP00000033193
annotation not available
    
 0.749
GLRX2
Glutaredoxin 2.
    
 0.742
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.