STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL5AADP-ribosylation factor-like protein 5A isoform X2; Belongs to the small GTPase superfamily. Arf family. (142 aa)    
Predicted Functional Partners:
ITSN2
Intersectin-2 isoform X1.
    
 0.961
ITSN1
Intersectin-1.
    
 0.944
GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1.
    
 0.930
ARFGAP1
ADP-ribosylation factor GTPase-activating protein 1 isoform X2.
   
 0.911
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.905
ARFGAP3
ADP-ribosylation factor GTPase-activating protein 3 isoform X1.
   
 0.877
PI4KB
Phosphatidylinositol 4-kinase beta isoform X1; Belongs to the PI3/PI4-kinase family.
    
 0.858
AP1G2
AP-1 complex subunit gamma.
    
 0.856
AP1G1
AP-1 complex subunit gamma.
    
 0.856
BBS7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 0.847
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.