Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KHD79225.1Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)    
Predicted Functional Partners:
KHD73977.1
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.906
KHD73981.1
Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
  
  
  0.878
KHD76259.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.810
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.724
KHD72239.1
Peptidase M50; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M50B family.
  
    0.715
KHD72707.1
Fructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.706
KHD74413.1
Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family.
   
 
 0.692
KHD76509.1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.691
pgi
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
    
 0.691
KHD78918.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.677
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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