STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD78948.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)    
Predicted Functional Partners:
KHD78073.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.713
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.685
KHD74539.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.685
KHD79268.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.654
KHD76966.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.654
KHD79064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.633
KHD78946.1
Peptidase M23B; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.612
KHD78947.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.612
KHD78942.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.552
KHD78944.1
Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.552
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.