Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KHD78968.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)    
Predicted Functional Partners:
mca
GlcNAc-PI de-N-acetylase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
       0.689
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.653
KHD72584.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.624
KHD78966.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.601
KHD74779.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.572
KHD73215.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.572
KHD79174.1
Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.568
KHD75208.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.504
KHD78911.1
PadR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.483
KHD73144.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.481
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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