Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
KHD78667.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (109 aa)    
Predicted Functional Partners:
KHD75150.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.959
KHD74168.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.888
KHD74165.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.887
KHD78666.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.867
KHD76799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.750
KHD75663.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.749
KHD78073.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.746
KHD78742.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.742
KHD73147.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.736
KHD78520.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.730
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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