STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD78517.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)    
Predicted Functional Partners:
KHD78518.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.830
KHD74589.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.743
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.730
KHD75208.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.708
hppA
Potassium transporter; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
       0.643
KHD78755.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.599
KHD74170.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.595
KHD72029.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.510
KHD76010.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.465
KHD76529.1
DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.423
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.