Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KHD78276.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)    
Predicted Functional Partners:
KHD78275.1
NADH:flavin oxidoreductase/NADH oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
KHD78124.1
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.700
KHD75560.1
Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.617
KHD78422.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.557
KHD75274.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.557
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
  0.497
KHD75879.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.485
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
  0.465
KHD74864.1
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
  0.465
KHD76817.1
Oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.428
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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