Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KHD78028.1Multidrug ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)    
Predicted Functional Partners:
KHD73102.1
Glutamate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     
0.887
KHD78027.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.840
KHD77017.1
Bacteriocin ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.730
KHD78257.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.691
KHD78261.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.691
KHD75799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.684
KHD75503.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.684
KHD78730.1
Arginine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     
0.664
KHD73830.1
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
  
 
 0.564
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 
  0.547
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.