Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KHD77628.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)    
Predicted Functional Partners:
KHD75799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.860
KHD75503.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.860
KHD72919.1
Topoisomerase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.692
KHD74009.1
Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
     
 0.671
KHD78258.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.666
KHD73939.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.631
KHD78257.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.627
KHD78261.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.627
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.618
whiB-6
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.551
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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