Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KHD77648.1Trp biosynthesis associated, transmembrane protein, oprn/chp; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
       0.817
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.817
KHD77641.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.542
KHD78284.1
Sporulation protein SsgA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.519
KHD77651.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
KHD77052.1
Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.489
KHD72618.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.489
KHD75229.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.463
KHD79040.1
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
KHD76041.1
Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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