Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KHD77040.1Anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)    
Predicted Functional Partners:
KHD77039.1
RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.979
KHD72491.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.730
KHD73830.1
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
   
    0.578
KHD75214.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.574
KHD78531.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.559
KHD77041.1
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
KHD77038.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
KHD72425.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.547
KHD74589.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.500
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
   
 0.475
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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