STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD76655.1N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)    
Predicted Functional Partners:
KHD74553.1
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.981
KHD73011.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.976
KHD76656.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.780
KHD75287.1
DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.681
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.680
KHD78870.1
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.494
selO
Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
       0.492
KHD74194.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.475
KHD78874.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.474
KHD76687.1
Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.458
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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