Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KHD76489.1Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)    
Predicted Functional Partners:
KHD73830.1
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
  
 0.736
KHD75711.1
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.668
KHD74933.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.615
KHD75799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.591
KHD75503.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.591
KHD75106.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.578
KHD76869.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.557
KHD76904.1
Glyoxalase/bleomycin resistance protein/dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.542
KHD73388.1
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.542
KHD75277.1
Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.526
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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