Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KHD76249.1Peptidase S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)    
Predicted Functional Partners:
KHD72705.1
Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.769
KHD77597.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.768
KHD75826.1
Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.754
KHD77382.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.687
KHD77551.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.674
KHD74776.1
Acetoin utilization protein AcuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.660
KHD73218.1
Acetoin utilization protein AcuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.660
KHD73739.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.654
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
  0.643
dnaJ-2
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
  0.643
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.