STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crgASeptation inhibitor protein; Involved in cell division; Belongs to the CrgA family. (87 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.864
KHD76307.1
Peptidoglycan glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.838
KHD77687.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.778
KHD77681.1
Peptidase S33; Essential cell division protein.
    
 
 0.769
whiA
Sporulation protein; Involved in cell division and chromosome segregation.
      
 0.754
KHD76301.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.656
KHD76310.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.634
KHD76573.1
Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
      
 0.594
KHD74865.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.570
KHD77677.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.