Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crgASeptation inhibitor protein; Involved in cell division; Belongs to the CrgA family. (87 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.674
KHD76307.1
Peptidoglycan glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.650
KHD77687.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.635
KHD76301.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.621
KHD77681.1
Peptidase S33; Essential cell division protein.
    
 
 0.585
whiA
Sporulation protein; Involved in cell division and chromosome segregation.
      
 0.570
KHD77677.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
tatA
Preprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
     0.557
KHD76310.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.541
KHD74865.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.493
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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