STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD75992.1DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1191 aa)    
Predicted Functional Partners:
KHD73011.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.966
KHD75991.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.948
KHD74553.1
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.919
KHD75989.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.915
KHD75990.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.915
KHD75988.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.904
KHD75994.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.844
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.680
KHD78870.1
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.614
KHD75993.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.