STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD75914.1Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dGTPase family. Type 2 subfamily. (488 aa)    
Predicted Functional Partners:
KHD76090.1
Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.947
KHD76509.1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.936
KHD73891.1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.931
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.930
KHD75913.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.734
KHD79130.1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.700
KHD77641.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
   
 0.556
KHD75981.1
Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.541
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.