Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KHD75925.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)    
Predicted Functional Partners:
KHD78865.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
KHD78486.1
DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
ligC
ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.986
ku
DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.906
ligB
ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
 0.827
KHD75924.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.757
KHD78608.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.713
KHD74621.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.695
KHD75923.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.618
KHD75982.1
RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.581
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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