Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KHD75952.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1043 aa)    
Predicted Functional Partners:
ruvA
ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
 
 0.976
ruvC
Hypothetical protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
 
 0.795
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.794
KHD74739.1
Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.777
KHD74608.1
Chemotaxis protein CheR; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.777
KHD73072.1
Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.777
KHD72532.1
Chemotaxis protein CheR; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.777
KHD72189.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.777
KHD74776.1
Acetoin utilization protein AcuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.766
KHD73218.1
Acetoin utilization protein AcuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.766
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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