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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD75952.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1043 aa)    
Predicted Functional Partners:
ruvA
ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
 
 0.992
KHD74739.1
Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.925
KHD74608.1
Chemotaxis protein CheR; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.925
KHD73072.1
Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.925
KHD72532.1
Chemotaxis protein CheR; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.925
KHD72189.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.925
ruvC
Hypothetical protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
 
 0.833
KHD76126.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.775
KHD75872.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.775
KHD72860.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.768
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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