Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
KHD75860.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (423 aa)    
Predicted Functional Partners:
KHD75861.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.747
KHD78073.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.736
KHD74164.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.720
KHD74574.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.705
KHD72625.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.702
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.695
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.671
KHD76366.1
Heat shock protein 90; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.667
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
   
 0.667
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.658
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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