Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KHD75219.1DNA-directed RNA polymerase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)    
Predicted Functional Partners:
KHD74164.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.687
KHD78073.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.676
KHD75836.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.643
KHD78804.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.609
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.590
KHD75245.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.576
KHD74548.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.573
KHD75599.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.556
KHD77910.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.551
KHD78627.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.547
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
Server load: low (12%) [HD]