STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD74991.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)    
Predicted Functional Partners:
KHD75799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.939
KHD75503.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.939
KHD78258.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.864
KHD76689.1
acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.785
KHD78073.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.767
KHD78257.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.765
KHD78261.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.765
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.760
KHD72582.1
AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.737
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.725
Your Current Organism:
Actinoplanes utahensis
NCBI taxonomy Id: 1869
Other names: A. utahensis, ATCC 14539, DSM 43147, IFO 13244, IMSNU 20044, JCM 3122, NBRC 13244, NRRL B-16727, VKM Ac-674
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