STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OFE15815.1hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)    
Predicted Functional Partners:
OFE16315.1
Fused acetyl/propionyl-CoA carboxylase subuit alpha/methylmalonyl-CoA decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.950
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.903
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.903
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
  
 0.874
OFE17069.1
Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.874
OFE14554.1
Carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.852
OFE15007.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.840
OFE14963.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.833
OFE14684.1
succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.830
OFE14610.1
succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.823
Your Current Organism:
Humibacillus sp. DSM 29435
NCBI taxonomy Id: 1869167
Other names: H. sp. DSM 29435
Server load: low (14%) [HD]