OFE16362.1 protein (Humibacillus sp. DSM 29435)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

OFE16362.1

Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (763 aa)

Predicted Functional Partners:

OFE15470.1

0.609

OFE16820.1

0.599

OFE16367.1

0.526

OFE18829.1

0.484

OFE15264.1

0.457

OFE16323.1

0.453

OFE15085.1

0.448

OFE17139.1

0.436

Your Current Organism:

Humibacillus sp. DSM 29435

NCBI taxonomy Id: 1869167
Other names: H. sp. DSM 29435

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OFE15085.1	OFE16362.1	BA895_08135	BA895_19295	Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.448
OFE15264.1	OFE15470.1	BA895_05800	BA895_05895	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.747
OFE15264.1	OFE16362.1	BA895_05800	BA895_19295	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.457
OFE15264.1	OFE17139.1	BA895_05800	BA895_16840	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.402
OFE15470.1	OFE15264.1	BA895_05895	BA895_05800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.747
OFE15470.1	OFE16362.1	BA895_05895	BA895_19295	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.609
OFE16323.1	OFE16362.1	BA895_19300	BA895_19295	Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.453
OFE16362.1	OFE15085.1	BA895_19295	BA895_08135	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.448
OFE16362.1	OFE15264.1	BA895_19295	BA895_05800	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.457
OFE16362.1	OFE15470.1	BA895_19295	BA895_05895	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.609
OFE16362.1	OFE16323.1	BA895_19295	BA895_19300	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	0.453
OFE16362.1	OFE16367.1	BA895_19295	BA895_19450	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.526
OFE16362.1	OFE16820.1	BA895_19295	BA895_04525	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.599
OFE16362.1	OFE17139.1	BA895_19295	BA895_16840	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.436
OFE16362.1	OFE18829.1	BA895_19295	BA895_01220	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.484
OFE16367.1	OFE16362.1	BA895_19450	BA895_19295	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.526
OFE16367.1	OFE17139.1	BA895_19450	BA895_16840	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.495
OFE16820.1	OFE16362.1	BA895_04525	BA895_19295	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.599
OFE17139.1	OFE15264.1	BA895_16840	BA895_05800	Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.402
OFE17139.1	OFE16362.1	BA895_16840	BA895_19295	Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.436

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.901

expected number of edges:

16

PPI enrichment p-value:

0.0428

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000155

Phosphorelay sensor kinase activity

4 of 33

1.66

1.33

0.0013

GO:0016772

Transferase activity, transferring phosphorus-containing groups

5 of 172

1.04

0.74

0.0060

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3388

Mixed, incl. Nucleotide cyclase, and MHYT domain

6 of 10

2.35

4.58

4.82e-10

CL:3391

MHYT domain, and PAC motif

4 of 5

2.48

3.25

6.14e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02030

Bacterial chemotaxis

3 of 29

1.59

0.99

0.0082

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

4 of 46

1.51

1.25

0.0013

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001789

Signal transduction response regulator, receiver domain

4 of 33

1.66

1.2

0.0029

IPR011006

CheY-like superfamily

4 of 34

1.64

1.19

0.0029

IPR029016

GAF-like domain superfamily

3 of 18

1.79

1.01

0.0102

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

3 of 23

1.69

0.91

0.0148

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

3 of 24

1.67

0.9

0.0148

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00448

cheY-homologous receiver domain

4 of 32

1.67

1.62

0.00023

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

3 of 16

1.85

1.47

0.00097

SM00388

His Kinase A (phosphoacceptor) domain

3 of 23

1.69

1.3

0.0017

SM00387

Histidine kinase-like ATPases

3 of 34

1.52

1.09

0.0038

SM00091

PAS domain

3 of 34

1.52

1.09

0.0038

(more ...)

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