Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)    
Predicted Functional Partners:
AKC95141.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
AKC95139.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.963
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
  
 0.953
AKC95160.1
Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.938
rbsK
Hypothetical protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.929
AKC95666.1
Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.926
AKC95899.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.926
AKC95002.1
Mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.916
AKC96033.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.910
AKC95032.1
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.908
Your Current Organism:
Sneathia amnii
NCBI taxonomy Id: 187101
Other names: Leptotrichia amnionii, S. amnii, Sneathia sp. Sn35, cf. Leptotrichia sp. AMN-1, strain Sn35
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