node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mlg_0545 | Mlg_0546 | Mlg_0545 | Mlg_0546 | Hypothetical protein. | PFAM: protein of unknown function DUF107; KEGG: tfu:Tfu_2226 putative integral membrane protein. | 0.484 |
Mlg_0545 | ilvC | Mlg_0545 | Mlg_0544 | Hypothetical protein. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.421 |
Mlg_0546 | Mlg_0545 | Mlg_0546 | Mlg_0545 | PFAM: protein of unknown function DUF107; KEGG: tfu:Tfu_2226 putative integral membrane protein. | Hypothetical protein. | 0.484 |
ilvC | Mlg_0545 | Mlg_0544 | Mlg_0545 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Hypothetical protein. | 0.421 |