STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlg_1416PFAM: thymidylate kinase; KEGG: pae:PA2962 thymidylate kinase. (217 aa)    
Predicted Functional Partners:
Mlg_1417
PFAM: aminodeoxychorismate lyase; KEGG: csa:Csal_1605 aminodeoxychorismate lyase.
 
  
 0.984
Mlg_1415
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: mca:MCA1995 DNA polymerase III, delta prime subunit.
 
 0.981
Mlg_2102
KEGG: mca:MCA1634 ribonucleoside-diphosphate reductase, alpha subunit; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit; PFAM: ribonucleotide reductase large subunit; ATP-cone domain protein; Ribonucleotide reductase large subunit, N terminal domain protein.
  
 
 0.960
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
  
 0.954
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.947
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.945
Mlg_1471
KEGG: mca:MCA2543 ribonucleoside reductase, intein-containing; TIGRFAM: Protein splicing (intein) site; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; SMART: Hedgehog/intein hint domain protein.
  
 
 0.941
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.935
Mlg_1418
Aminodeoxychorismate lyase apoprotein; PFAM: aminotransferase, class IV; KEGG: pae:PA2964 4-amino-4-deoxychorismate lyase.
 
  
 0.934
Mlg_2103
PFAM: ribonucleotide reductase; KEGG: rpc:RPC_3518 ribonucleoside-diphosphate reductase.
  
 
 0.932
Your Current Organism:
Alkalilimnicola ehrlichii
NCBI taxonomy Id: 187272
Other names: A. ehrlichii MLHE-1, Alkalilimnicola ehrlichii MLHE-1, Alkalilimnicola ehrlichii str. MLHE-1, Alkalilimnicola ehrlichii strain MLHE-1, Mono Lake Gammaproteobacter MLHE-1, arsenite-oxidizing bacterium MLHE-1, gamma proteobacterium MLHE-1
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