STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (540 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
 
 0.975
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.939
Mlg_0825
dCTP deaminase; KEGG: bbr:BB0845 deoxycytidine triphosphate deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase.
  
 
 0.921
Mlg_2766
PFAM: NUDIX hydrolase; KEGG: tbd:Tbd_2635 hypothetical protein.
  
 
 0.918
Mlg_1457
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mag:amb2392 predicted pyrophosphatase.
    
  0.913
rpsB
PFAM: ribosomal protein S2; KEGG: pae:PA3656 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.909
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.877
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.868
Mlg_2774
KEGG: mca:MCA3089 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase.
  
  
 0.863
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.861
Your Current Organism:
Alkalilimnicola ehrlichii
NCBI taxonomy Id: 187272
Other names: A. ehrlichii MLHE-1, Alkalilimnicola ehrlichii MLHE-1, Alkalilimnicola ehrlichii str. MLHE-1, Alkalilimnicola ehrlichii strain MLHE-1, Mono Lake Gammaproteobacter MLHE-1, arsenite-oxidizing bacterium MLHE-1, gamma proteobacterium MLHE-1
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