Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BN69_0807Cytochrome C biogenesis protein; Possible subunit of a heme lyase. (154 aa)    
Predicted Functional Partners:
BN69_0808
Cytochrome c-type biogenesis protein CcmF.
 
  
 0.969
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.920
BN69_1961
Periplasmic protein thiol/disulfide oxidoreductase DsbE.
 
  
 0.910
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.874
BN69_0787
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
   
 0.839
BN69_0810
Cytochrome c-type biogenesis protein CcmI.
 
  
 0.814
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.743
BN69_0806
Conserved hypothetical protein.
       0.541
BN69_0805
Monooxygenase, FAD-binding.
       0.527
BN69_2288
Redoxin domain protein.
 
  
 0.408
Your Current Organism:
Methylocystis sp. SC2
NCBI taxonomy Id: 187303
Other names: M. sp. SC2
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