Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
BN69_1972OmpA/MotB domain protein. (284 aa)    
Predicted Functional Partners:
BN69_2175
OmpW family protein.
   
 0.867
BN69_2398
Polysaccharide export protein.
   
 0.818
BN69_1907
TonB-dependent receptor.
  
  
 0.734
tolB
Protein tolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.727
BN69_2867
Conserved hypothetical protein.
   
 0.700
BN69_2496
Hemolysin-type calcium-binding region.
   
 0.599
BN69_2498
Putative hemolysin-type calcium binding protein.
   
 0.599
BN69_1973
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
       0.596
BN69_2466
Putative alpha amylase domain-containing protein.
     
  0.584
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
     
 0.567
Your Current Organism:
Methylocystis sp. SC2
NCBI taxonomy Id: 187303
Other names: M. sp. SC2
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