STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQQ05600.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)    
Predicted Functional Partners:
gcvT_1
Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
  
 
 0.918
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.917
AQQ03045.1
Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.917
gcvT_5
Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
  
 0.916
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
 
 0.913
hemA_1
5-aminolevulinic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.913
gcvPB
Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.909
gcvPA
Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
    
  0.908
soxA_2
FAD-binding oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.907
soxB
Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.907
Your Current Organism:
Labrenzia aggregata
NCBI taxonomy Id: 187304
Other names: ATCC 25650, Agrobacterium aggregatum, DSM 13394, IAM 12614, JCM 20685, L. aggregata, LMG 122, LMG:122, NBRC 16684, NCIMB 2208, Stappia aggregata, strain B1
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