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glnD protein (Yersinia pestis KIM10) - STRING interaction network
"glnD" - PII uridylyl-transferase in Yersinia pestis KIM10
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glnDPII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism (912 aa)    
Predicted Functional Partners:
glnB
Nitrogen regulatory protein P-II (112 aa)
 
  0.990
glnK
Nitrogen regulatory protein P-II 2 (112 aa)
 
  0.989
glnE
Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Adenylation and deadenylation of glutamate--ammonia ligase (951 aa)
   
   
  0.952
ampM
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (263 aa)
   
        0.908
glnA
Glutamine synthetase (477 aa)
 
     
  0.900
glnR
Nitrogen regulation protein NR(II) (349 aa)
   
 
 
  0.863
YPO3557
Glutamate synthase subunit alpha (1485 aa)
         
  0.828
amtB
Ammonium transporter (431 aa)
 
     
  0.710
dapD
2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase (274 aa)
         
  0.702
glnG
Nitrogen regulation protein NR (470 aa)
   
   
  0.661
Your Current Organism:
Yersinia pestis KIM10
NCBI taxonomy Id: 187410
Other names: Y. pestis KIM10+, Yersinia pestis KIM, Yersinia pestis KIM10, Yersinia pestis KIM10+, Yersinia pestis str. KIM10+, Yersinia pestis strain KIM10+
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