STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_104Multidrug transporter homolog; Function Code:12.11 - Cell Processes, Detoxification; similar to, sp:LN:TCRB_BACSU AC:P23054, p()=2.8E-26, pid=24%. (459 aa)    
Predicted Functional Partners:
MTH_546
Cationic amino acid transporter related protein; Function Code:12.01 - Cell Processes, Transport of amino acids--peptides and amines; similar to, sp:LN:YW19_MYCTU AC:Q10858, p()=2.7E-19, pid=22%.
 
 
 0.529
MTH_105
Glutamate synthase (NADPH), alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:F64468 AC:F64468, p()=7E-77, pid=33%; Belongs to the glutamate synthase family.
  
  
 0.522
MTH_106
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64446 AC:B64446, p()=4E-12, pid=32%.
       0.464
dnaJ
DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
 
 
 0.458
MTH_1687
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64416 AC:G64416, p()=9E-17, pid=31%.
   
    0.426
MTH_1688
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64416 AC:G64416, p()=2.3E-11, pid=39%.
   
    0.426
MTH_792
3-hydroxy-3-methylglutaryl-CoA-synthase; Function Code:3.04 - Lipid Metabolism, Sterol biosynthesis; similar to, pir:LN:A64493 AC:A64493, p()=8.6E-131, pid=68%; Belongs to the thiolase-like superfamily. UPF0219 family.
 
  
 0.423
MTH_107
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64493 AC:H64493, p()=0.000066, pid=14%.
     
 0.407
MTH_1726
Citrate synthase I; Function Code:1.02 - Carbohydrate Metabolism, Citrate cycle (TCA cycle); similar to, sp:LN:CYSZ_CUCMA AC:P49299, p()=1.6E-15, pid=28%.
  
 
 0.406
MTH_962
Citrate synthase I; Function Code:1.02 - Carbohydrate Metabolism, Citrate cycle (TCA cycle); similar to, sp:LN:CYSZ_CUCMA AC:P49299, p()=6.4E-16, pid=30%.
  
 
 0.406
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.