STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
MTH_105Glutamate synthase (NADPH), alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:F64468 AC:F64468, p()=7E-77, pid=33%; Belongs to the glutamate synthase family. (622 aa)    
Predicted Functional Partners:
MTH_191
Glutamine PRPP amidotransferase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:PUR1_SYNP7 AC:Q55038, p()=1.7E-21, pid=22%.
 
 
 0.986
MTH_106
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64446 AC:B64446, p()=4E-12, pid=32%.
  
 0.984
MTH_192
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64446 AC:B64446, p()=0.0000024, pid=20%.
  
 0.982
fmdC
Molybdenum formylmethanofuran dehydrogenase, subunit C; Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidize formylmethanofuran. This enzyme is oxygen-labile. In the N-terminal section; belongs to the FwdC/FmdC family.
 
 
 0.919
fwdC
Tungsten formylmethanofuran dehydrogenase, subunit C; Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidize formylmethanofuran. This enzyme is oxygen-labile. Belongs to the FwdC/FmdC family.
 
 
 0.912
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
  
 0.900
MTH_238
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64382 AC:B64382, p()=7.3E-70, pid=31%; To M.jannaschii MJ0658.
  
 
 0.859
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
  
  
 0.856
MTH_978
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:B64476 AC:B64476, p()=7.5E-77, pid=37%; Belongs to the aldehyde dehydrogenase family.
  
  
 0.840
MTH_476
Pyruvate dehydrogenase / acetolactate synthase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1881244 LN:AB001488, p()=1.8E-84, pid=32%; Belongs to the TPP enzyme family.
  
  
 0.826
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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