STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queCConserved protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (222 aa)    
Predicted Functional Partners:
queE
Coenzyme PQQ synthesis protein III; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.996
queD
Conserved protein; Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
 
  
 0.996
MTH_1109
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64473 AC:B64473, p()=2.2E-45, pid=27%; Belongs to the LarC family.
       0.919
MTH_1110
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64455 AC:C64455, p()=4.7E-20, pid=30%; To M.jannaschii MJ1244 and MJ1245.
       0.773
MTH_287
Anaerobic ribonucleoside-triphosphate reductase activating protein; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:NRDG_BPT4 AC:P07075, p()=3.1E-16, pid=22%.
  
  
 0.763
tgtA
tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
     
 0.728
MTH_1539
Anaerobic ribonucleoside-triphosphate reductase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64403 AC:H64403, p()=2.5E-200, pid=51%.
       0.611
cobS
Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
     
 0.600
MTH_1111
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:A64466 AC:A64466, p()=6.3E-25, pid=24%.
       0.582
MTH_1229
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64400 AC:E64400, p()=2.5E-28, pid=34%.
 
     0.578
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.