STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1128Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64493 AC:F64493, p()=0.00000001, pid=38%. (64 aa)    
Predicted Functional Partners:
cdhD
Corrinoid/iron-sulfur protein, small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
  
    0.743
MTH_1711
Nitrogenase reductase related protein; Function Code:2.06 - Energy Metabolism, Nitrogen metabolism; similar to, pir:LN:E64385 AC:E64385, p()=1.6E-65, pid=50%.
  
    0.605
MTH_1302
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y106_METJA AC:Q57570, p()=1.3E-31, pid=30%.
      
 0.570
mtrA1
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
      
 0.523
cdhE
Corrinoid/iron-sulfur protein, large subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
    0.506
MTH_1714
Formate hydrogenlyase, iron-sulfur subunit 2; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D64319 AC:D64319, p()=4.6E-29, pid=37%.
  
    0.450
gap
Glyceraldehyde 3-phosphate dehydrogenase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:S02804 AC:S02804, p()=7.6E-139, pid=76%.
       0.436
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.418
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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